Half Life Of Advair Diskus
No terminal half life estimates were calculated for salmeterol following administration of advair hfa.
Half life of advair diskus. The xinafoate moiety is highly protein bound 99 and has a long elimination half life of 11 days. Your healthcare provider may also prescribe advair for other purposes not discuss in this medication guide. The terminal elimination half life was about 5 5 hours 1 volunteer only.
132 the terminal half life of fluticasone propionate averaged 5 33 to 7 65 hours when advair 133 diskus was administered which is similar to that reported when fluticasone propionate was 134 given. In 2 healthy adult subjects who received 1 mg of radiolabeled salmeterol as salmeterol xinafoate orally approximately 25 and 60 of the radiolabeled salmeterol was eliminated in urine and feces respectively over a period of 7 days. The xinafoate moiety has no apparent pharmacologic activity.
It is generally prescribed to patients whose asthma symptoms are not easily managed by other short acting inhalers.
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